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Posts Tagged ‘cancer’
Wednesday, January 20th, 2010
A recent (1/18/2010) article published in JAMA (The Journal of the American Medical Association) showed that the costs of brand-name treatments for psoriasis rose by an average of 66% between 2000 and 2008!
Average annual phototherapy costs ranged from $3,083 to $7,288, while biologic therapies ranged from $18,284 to $27,577 annually.
To put that into perspective, the lowest average amount paid annually for biologic treatments is roughly three times the cost of a 16-lamp UVBioTek home phototherapy system… a one-time expense that provides a lifetime of effective treatments – compared with $20K-$30K every year for biologic therapies.
For those few people for whom phototherapy is ineffective, or just not effective enough, biologics are virtual "miracle drugs" where the benefits almost outweigh the rather sizable risks for internal organ damage, cancer and other systemic side effects. But when phototherapy can be used instead, a home system would save over a quarter of a million dollars for each and every patient after just ten years!!
That article can be found here: Science Daily (1/20/2010)
Interestingly, the Archives of Dermatology has also summarized the very same article, with one notable exception; they removed all references to phototherapy! Ask your dermatologist whose interests they have in mind; your's or their pharmaceutical rep's… These numbers seem to point in the wrong direction.
Tags: biologicals, cancer, medical insurance, narrowband, phototherapy, psoriasis, UVBioTek Posted in News | 15 Comments »
Thursday, September 3rd, 2009
The use of ‘biological’ medications such as Enbrel, Humira, Raptiva and others have been used to treat psoriasis at a phenomenal rate . In 2008, the entire psoriasis market represented ~$2.5 billion. 55%, or $1.4 billion was spent on biological meds alone.
Aside from the known risks these medications present for cancer and other serious side effects, a large percentage of those patients would likely see better results with phototherapy and without increasing the hazards associated with biological medications. Many patients find that they can get and stay clear with phototherapy alone, without using the expensive and potentially risky biological medications. Sadly, too many dermatologists are prescribing biologicals without ever seeing if phototherapy would be effective first.
The cost of a home narrowband (nbUVB) system is often less than a single month’s worth of biological meds, yet it will provide a time-tested, virtually side-effect free therapy for decades with no additional costs to the patient OR the insurers. Instead, more than half of all the money spent in treating psoriasis is going to the pharmaceutical companies on a regular, routine schedule. This ensures a steady revenue stream, but at the expense of the patient’s best interests.
If just half of the patients who used biological meds in 2008 had instead purchased home nbUVB systems, it could have reduced the overall amount of money spent on psoriasis by a billion dollars annually… while providing more patients with more satisfying, trouble-free results.
(reference: http://www.researchandmarkets.com/research/b8d445/commercial_insight)
Tags: biologicals, cancer, health insurance, home, narrowband, nbUVB, phototherapy, psoraisis, UVB, UVBioTek, vitiligo Posted in Basic information, News | 9 Comments »
Monday, August 10th, 2009
The FDA has issued a warning that TNF blockers (including Enbrel, Humira, Remicade and others) may cause lymphoma, leukemia and other cancers in children and teens. This is in addition to the "black box" cancer warning such medications already carry.
You can read it from the FDA’s website here: FDA:
Cancer Warnings Required for TNF Blockers
And this is the information they offer to healthcare providers:
Information for Healthcare Professionals
These medications certainly still have their uses, but a very large number of people who are currently on Biological meds could probably be seeing good results with narrowband UVB phototherapy instead, without such established links to cancer and without stressing the internal organs.
Treat lightly instead…
Tags: biologicals, cancer, children, enbrel, fda, humira, leukemia, lymphoma, remicade, teenagers, warning Posted in News | 12 Comments »
Tuesday, August 4th, 2009
Short answer: Not likely.
The American Academy of Dematology recently declared UV light to be a carcinogen. That means they believe that exposure to UV light can lead to an increased risk for cancer. However, this does not mean you will get cancer if you are exposed to UV light. Like so many things, UV light has the potential to increase your risk for cancer when you get more than your skin is capable of handling; this usually results in sunburns of varying degrees of severity.
The more often you get sunburned, and the worse those sunburns are, the greater your risk for skin cancer becomes. Does that mean if you avoid UV light you will not get cancer? Far from it. In fact, there are all kinds of problems that are caused by not getting enough UV light and there are many other things that are known to elevate your cancer risk. The secret is, as with so many things, moderation. Virtually all medications are toxic, if taken in large enough doses. Determining the proper dosage is always a balance between figuring out how much is too much and how much is not enough. If you properly follow the directions, you will receive the benefits. Phototherapy is no different than any other medication in this regard.
When the body is exposed to UV light (like anytime you’re in sunlight) it causes several things to happen. Right away it allows and is required for the body to properly process Vitamin D, which is directly related to bone strength and general health. The next thing that happens is the skin cells near the surface (the ones being most exposed) get irritated by the light and call for something known as "melanin". Melanin is what gives our skin color. The condition that causes a complete lack of melanin is commonly known as "albinism".
The nucleus of our cells contains DNA. If our DNA gets damaged, it can cause unpredictable effects. Usually such damage just causes the cell to die off and be replaced; in fact, this happens all the time. But every so often, and for reasons that nobody fully understands, such cells can become cancerous. In order to protect the nucleus, melanin is delivered to the exposed skin cells and collects above the cell’s nucleus to shield it from the the UV light – just like sunglasses.
The production of melanin in response to UV exposure is a natural, normal, protective process. Tanning does for our body what the ozone layer does for the planet. It shields us from much of the UV light. When you develop a tan, your skin is responding properly to its environment. However, if you get too much UV too quickly, you end up actually killing skin cells; we experience this as a sunburn. Unlike the tan response, a sunburn is not a protective reaction. Instead, it is simply the body’s response to cellular damage.
The proper use of UVB phototherapy calls for regular exposure to slightly less UV than what would cause you to burn. If you are properly following the protocol, you will avoid getting burned.
What that all comes down to is that no link has ever been established between the proper use of UVB phototherapy and an increase in the risk for skin cancer, and that’s over nearly a century of therapeutic usage. It does not stress the internal organs the way many internal medications frequenty do. There is no safer form of therapy.
So the problem does not really appear to be with UV light exposure, but with UV light OVER-exposure. That can subsequently lead to a burn, which can leads to cellular damage, which can lead to cancer. The solution, as with so many things in life, is not to avoid all UV light, but simply to avoid getting burned. That can easily be done by following the standard treatment protocol developed by the National Psoriasis Foundation.
Tags: burn, cancer, carcinogenic, DNA, exposure, melanin, narrowband, nbUVB, phototherapy, ultraviolet, UVB, UVBioTek Posted in Basic information | 103 Comments »
Tuesday, August 4th, 2009
Phototherapy refers to medically therapeutic exposure to light, or using light to treat medical problem. Ultraviolet (UV) light is most frequently used, and it is broken down into three band-ranges. the A range (the "colors" that generate suntans; ~320-400 nm), the B range (the "colors" that can cause sunburns; ~290-320 nm), and the C range (the "colors" that are lethal to most living things; ~100-250 nm); these bands are also known as UVA, UVB and UVC.
While UVC lights are used in a variety of air & water purification and sterilization systems, there are currently no therapeutic uses for UVC light; it is simply too intense.
UVA lamps are most commonly used in tanning systems, but they are also used medicinally for what’s called "PUVA" therapy. For decades, PUVA was the only effective treatment for many people.
Too much UVB light and you’ll quickly get a sunburn, but when carefully administered it can be the solution for millions of people suffering with psoriasis, along with a long list of other conditions.
Within the UVB range, there is a very specific frequency range that appears to be what most skin problems are thirsty for; this is called "Narrowband UVB" (nbUVB; 311-313 nm) and it is effective for roughly 80% of all applicable patients. Its only side effects are sunburns (if you over-do it) and cataracts (if you don’t shield your eyes). While a history of moderate to severe sunburns has been linked to an increased risk for certain skin cancers, the proper use of UVB light has never been shown to increase the risk for skin cancer; and that’s with almost a century of medical use.
Phototherapy, specifically nbUVB, is most often used to treat conditions like psoriasis, vitiligo and eczema. Less common problems that respond well to nbUVB are certain types of dermatitis, prurigo, porphyria, pruritis, a form of cancer usually called CTCL (Cutaneous T-Cell Lymphoma). And phototherapy is safe enough to be used with pregnant women and children.
The basic goal behind nbUVB therapy is determining how much light exposure causes your skin to burn by slowly increasing your exposure amounts untill your skin begins to burn. You take treatments that are just below that amount every other day (at most) until you are clear again following the basic protocol developed by the National Psoriasis Foundation.
Tags: cancer, CTCL, narrowband, phototherapy, porphyria, pruritis, psoraisis, UVB, vitiligo Posted in Basic information | 13 Comments »
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